Karolinska Institutet Open Archive
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Clinical and radiological features of thoracic aortic disease
(Inst för molekylär medicin och kirurgi / Dept of Molecular Medicine and Surgery, 2024-05-14)Background The pathologies of the aorta constitute a group of severe diseases often managed by means of a single variable, the maximum aortic diameter. This variable is insufficient, and the aim of this work is ... -
Decoding the symphony : illuminating the mammalian mitochondrial RNA binding proteome with a novel interactome approach
(Inst för medicinsk biokemi och biofysik / Dept of Medical Biochemistry and Biophysics, 2024-05-14)Mitochondria, colloquially known as the "powerhouses of the cell" are crucial for generating cellular energy through a process known as oxidative phosphorylation (OXPHOS). These minute but mighty organelles are distinct ... -
Biomarkers in hepatocellular carcinoma
(Inst för medicin, Huddinge / Dept of Medicine, Huddinge, 2024-05-13)Hepatocellular carcinoma (HCC) is the most common primary liver cancer. Globally in 2020, liver cancer were the seventh most common cancer form and the second most common form of cancer related death. Early HCCs are often ... -
Aspects on diabetes and diet with special focus on carbohydrates : epidemiological and clinical studies
(Inst för molekylär medicin och kirurgi / Dept of Molecular Medicine and Surgery, 2024-05-13)Carbohydrate intake affects blood glucose levels more than any other dietary factor, providing a conceptually promising area of research in the prevention and management of diabetes. Intake of fruit and vegetables, a ... -
Evaluation of new and current preventive strategies for cervical and vaginal cancer
(Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2024-05-08)This thesis addresses clinical research questions on primary and secondary prevention of cervical and vaginal cancer by targeting four groups of women in the organized cervical screening program; women entering the screening ...