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Modeling disturbances of cholinergic systems : possible relevance for schizophrenia
(2005-11-25)
projects has been to evaluate if disturbances in central cholinergic function can contribute to schizophrenic symptoms. In all studies an immunotoxin, 192 IgG-saporin (192-sap), was used to selectively kill cholinergic neurons in the basal forebrain...
Myasthenia gravis : clinical aspects and possible involvement of prolactin
(2006-09-15)
with raised levels of plasma PRL in female patients. Since PRL has stimulating effects on the immune system, the increased levels might be implied in the pathophysiology of MG. A case control study of PRL levels was performed in 192 MG patients and 192 healthy...
Drug metabolic capacity in Koreans : CYP2D6 & CYP2C19 pheno- and genotype relationships in healthy volunteers and in patients
(2002-05-24)
.6%) were identified as poor metabolizers with MR of 6.95 or higher. Allele frequencies of CYP2C19*2 and *3 were 21% and 12%, respectively. The distributions of the omeprazole MRs significantly depend on CYP2C19 genotype status (p<0.0001).
One hundred...
Gonad development and male gametogenesis
(2002-01-25)
containing at least one functional spermatogenesis gene. To establish the prevalence of clinically relevant Y chromosome microdeletions among infertile men, we screened 192 men with disturbed spermatogenesis. Of these 192, 139 were azoospermic and 53...
Targeting non-receptor tyrosine kinases using small molecule inhibitors : an overview of recent advances
(2015-12-28)
Protein tyrosine kinases are enzymes that catalyze the transfer of phosphate groups from ATP to tyrosine residues on other proteins as substrate. Phosphorylation at tyrosine residues regulates several functions, including ...
Metastatic bone disease
(2000-01-21)
be ascertained. For patients with a suspected skeletal metastasis the search for the primary tumor may preferably start with FNAB.
Surgical treatment: Risk factors for failure after operation for pathologic fractures were identified in 192 patients treated...
Juvenile and adult criminality : relationships to platelet MAO activity, triiodothyronine, ADHD, conduct disorder and psychopathy
(1996-03-29)
Indicators for persistent risk criminality in a group of grown up juvenile delinquents were investigated. The subjects had been examined In 'Young Lawbreakers': a study of 192 boys from an urban area, aged 11-14 years in 1959-1963. They had...
Metabolic syndrome and esophageal and gastric cancer
(2016-12-20)
adenocarcinoma were identified from the Norwegian Cancer Registry. Hazard ratios (HRs) and 95% confidence intervals (CIs) were estimated using Cox proportional hazard models with adjustment for potential confounders.
RESULT: Among 192,903 participants followed...
Fetal and early life antibiotics exposure and very early onset inflammatory bowel disease : a population-based study
(British Society of GastroenterologyBMJ Publishing Group, 2018-01-11)
.48 (95% CI 1.01 to 6.08) for CD and 1.25 (95% CI 0.47 to 3.26) for UC, respectively. For antibiotics in infantile age, the aHR for IBD was 1.11 (95% CI 0.57 to 2.15); for CD 0.72 (95% CI 0.27 to 1.92) and 1.23 (95% CI 0.45 to 3.39) for UC. Excluding...