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Studies of VEGF-B and novel PDGFs in tumorigenesis and angiogenesis
(2004-02-06)
novel PDGF family members, PDGF-C and PDGF-D in tumor growth and tumor angiogenesis.
Characterization of the expression pattern of two isoforms of VEGF-B, VEGF-B167 and VEGF-B186 in tissues and cell lines indicate that VEGF-B167 is the predominant...
Studies of the vascular endothelial growth factors, VEGFs, and their receptors, focusing on VEGF-B
(1999-05-19)
release and bio-availability. While VEGF-B167 is non-glycosylated, highly basic and retained at the cell surface upon secretion, VEGF-B186 is O-linked glycosylated and readily secreted from cells. Both isoforms of VEGF-B were found to specifically bind...
Isolation and characterization of novel intestinal polypeptides of the enteroinsular and brain-gut axes and of macrophages
(1997-11-21)
describes the isolation and characterization, from intestinal tissues, of seven polypeptides, five porcine [daintain/AIF1, diazepam binding inhibitor (DBI), dopuin, pancreatic polypeptide (PP), vimentin-37] and two from chicken (DBI1-86 and DBI35...
Asthma and height in twins : a cohort and within-pair analyses study
(2017-06-14)
, no statistically significant associations were found between current asthma and puberty/menarche. Boys with asthma were shorter than boys without asthma at 8-9 years (on average, 1.86 [0.17-3.56] cm, p = .03) and at 13-14 years (on average, 2.94 [0.98-4.91] cm, p...
On the pro-apoptotic signaling induced by interferon-alpha
(2007-04-06)
Interferon-alpha (IFNalpha) is a pleiotropic cytokine which has been used
as an active drug in the treatment of malignant diseases for almost five
decades. It has shown beneficial results in several hematological
malignancies, ...
Alzheimer's disease mutations and cellular signalling
(2001-11-16)
Alzheimer's disease is the most frequent cause of dementia in elderly and is characterised neuropathologically by the extracellular deposition of amyloid plaques (containing the 39-43 amino acid Abeta peptide), as well as ...
Dendritic cell and IgA responses in SIV and HIV-1 pathogenesis
(2004-04-28)
Simian immunodeficiency virus (SIV) as well as human immunodeficiency virus (HIV-1) can infect different subsets of dendritic cells (DC). Such cells may therefore not only be involved in the generation of recruitment of ...
T lymphocytes in Wegener’s granulomatosis
(2000-09-08)
Wegener's granulomatosis (WG) is a systemic necrotizing vasculitis that
affects small and medium size blood vessels. The respiratory tract and
lungs are usually compromised with necrotizing granulomatous formations.
The ...
Genetic analysis of type 1 diabetes susceptibilty
(2008-11-21)
Type 1 diabetes (T1D) is a multifactorial disease where the pancreatic beta-cells are destroyed in an autoimmune attack. For the patients, this in turn leads to lifelong daily insulin treatment and increased risk for various ...