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Genetic analysis of type 1 diabetes susceptibilty
(2008-11-21)
candidate genes: Ringfinger protein 180 (RNF180) and 5-hydroxytryptamine (serotonin) receptor 1A (HTR1A). We have confirmed the association of these genes in Danish families. These genes are in strong linkage disequilibrium with each other but in preliminary...
Articular distension in arthroscopy : an experimental study on intra- and extra-articular effects of pressure
(1997-03-21)
rupture.
Using the duplex ultrasound technique, the flow velocity, diameter and cross sectional area of the great saphenous vein and one of the postelior tibial veins of the lower leg were recorded during knee arthroscopy at 0, 100 and 180 mmHg IAP...
Immunoregulation of experimental autoimmune neurirtis focuses on cell immunity
(2003-02-07)
-deficient mutant (IFN-gammaR-/-) and wild-type mice immunized with PO peptide 180-199. IFN-gammaR-/- mice exhibited later onset, less severity of clinical disease accompanying with less infiltration of inflammatory cells and demyelination compared with wild type...
Genomic studies of expanded trinucleotide repeats : focus on neuropsychiatric disorders
(1998-08-14)
) and spinocerebellar ataxia type 7 (SCA7) belong to a group of autosomal dominant cerebellar ataxias showing progressive degeneration of cerebellar pathways as well as anticipation. CAG/CTG RED products of 180-270 nt were associated with disease in five families...
Cumulative assessment of persistent organic pollutant toxicity in vivo
(2011-05-02)
-specific cumulative assessment based on effects considered as markers of DL toxicity observed for different POPs in vivo. The studies focused on PCB 180 (Paper I), which is not included in the TEF concept, and the commercial penta-BDE mixture Bromkal 70-5DE (Paper II...
Role of phospholipids in neurodegenerative diseases
(1997-05-19)
subclass changed. PE-plasmalogen showed a decrease in oleic and polyunsaturated fatty acids and displayed a shift ofthe aldehyde pattern from 18:1 to 18:0. In liposomal systems, plasmalogens effectively protected poly unsaturated fatty acids from iron...
Blood pressure and dementia in the very old : an epidemiologic study
(1998-03-03)
pathophysiological change in a dementia process, particularly Alzheimer's disease; 2) clinically unrecognized vascular lesions in the brain or atherosclerosis are responsible for both dementia and BP reduction. In addition, baseline systolic BP >180 mm Hg...
The importance of the CYP2C19 polymorphism for disposition and effects of omeprazole treatment
(1999-05-20)
. pylori infection had an additional gastrin increasing effect but did not significantly influence intragastric acidity.
Serum gastrin, pepsinogen I and plasma chromogranin A were assessed in 180 patients with acid related disorder of different CYP2C19...
Epidemiological and recovery facilitating studies of an urban population of stroke patients in Iran
(2010-05-28)
. Stroke patients were enrolled within 15 to 180 days after stroke onset. Motor function, ADL, stroke severity, mood, and cognition were assessed by Fugl-Meyer (FM), Barthel Index (BI), National Institute of Health Stroke Scale (NIHSS), Geriatric Depression...