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Liver tumour promoting effects by polychlorinated biphenyls
(1998-11-13)
and foci occurrence for the selection of growth parameters in the model.
The tumour promoting potency of two PCB congeners, 2,3,4,5,3',4'-hexachlorobiphenyl (PCB156) and 2,4,5,3',4'-pentachlorobiphenyl (PCB118), was studied individually in a two...
Application of the benchmark dose-response modelling approach for risk characterization of chemicals
(2022-04-28)
in the organs of rats were demonstrated employing the BMD dose-response modelling approach, revealing that the apolar liver retinoid concentrations were the most sensitive endpoint. The retinoid system was shown to be sensitive to PCB-156 exposure...
Chronic leukemic B-cell disorders and trisomy 12 : a study of surface markers, protein expression and clinical course
(2001-03-16)
with trisomy 12 from
a biological, clinical, and prognostic perspective.
Totally 156 patients with CLBD were evaluated for the occurrence of
trisomy 12. The findings were correlated with the morphology of the
leukemic cells and the surface expression of CD25...
Giardiasis in Leon, Nicaragua : prevalence and protection
(2006-11-20)
conditions. In a subsequent study a prevalence of 15.6 % of anti-Giardia antibodies in milk was detected in lactating women.
The protective effect of milk anti-Giardia antibodies against G. intestinalis infection was studied in 307 children aged 1 week...
Regulation of insulin-like growth factor-II in human liver
(2006-09-02)
4 different promoters. Transcripts derived from each promoter give rise to the same translated pro-IGF-II of 156 amino acids, which is sequentially processed into mature IGFII of 67 amino acids. Since the liver is an important site of IGF...
Depression or anxiety in adult twins is associated with asthma diagnosis but not with offspring asthma
(2017-01-17)
: We found an association between asthma and CES-D, major depression and GAD, for example adjusted OR for major depression and register-based asthma 1.56 (1.36-1.79). Most of the point estimates remained in the co-twin control analysis, indicating...
Genetic approaches towards understanding penumococcal virulence and biology
(2007-11-29)
obtaining the type 14 capsule. The rise seen in PNSP of serotype 14 could be attributed to this clone, known as Spain9V-3 of ST156. We also showed that about 50% of all PNSP in 2003 belonged to this clonal cluster and that its success may be explained...
Insight into the genetic characteristics of pneumococcal isolates
(2008-08-29)
is highly correlated to virulence in vivo. This was true for clinical isolates as well as constructed mutants. We also determined that the internationally successful clone of ST156 (Spain9V-3) constitute around 50% of all PNSP (penicillin non...
Regulation of TNF-alpha : implications for health and disease
(2003-05-23)
studies in human HepG2 cells. Allele frequency for the rare A- allele was 17% amongst 254 apparently healthy men of Swedish origin, aged 35-50 years. In 156 men, carriers of the rare allele had significantly lower TNF-alpha serum levels (p<0...