Karolinska Institutet Open Archive
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Tumour-draining lymph nodes in head and neck cancer : immunological signatures and clinical implications
(Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2024-05-23)The lymphatic system is responsible for orchestrating immune responses, particularly in cancer. Oral squamous cell carcinoma (OSCC) represents a significant clinical challenge, with lymphatic metastasis being a crucial ... -
Socioeconomic determinants of quality of care and outcomes in multiple sclerosis
(Inst för klinisk neurovetenskap / Dept of Clinical Neuroscience, 2024-05-22)Background: Multiple sclerosis (MS) is a chronic, inflammatory disease affecting the central nervous system (CNS), leading to varying degrees of neurological disability. While disease-modifying treatment (DMT) can ... -
Antibiotics in pregnancy : utilization, determinants and safety
(Inst för medicin, Solna / Dept of Medicine, Solna, 2024-05-22)Antibiotics are indispensable in maternal health. Crucial for treating and preventing bacterial infections ranging from common ailments to life-threatening conditions, antibiotics are inevitably prescribed to pregnant ... -
Lentigo maligna melanoma, a clinicopathological and grenz rays management study
(Inst för onkologi-patologi / Dept of Oncology-Pathology, 2024-05-22)Lentigo maligna (LM), a neoplastic proliferation of skin melanocytes, is the in situ form of lentigo maligna melanoma (LMM) and it was first described in 1892 by a british surgeon Sir Jonathan Hutchinson. LM and LMM are ... -
Exploring synbiotic treatment in ADHD, and immune-mediated prenatal risks for neurodevelopmental disorders
(Inst för molekylär medicin och kirurgi / Dept of Molecular Medicine and Surgery, 2024-05-22)The etiologies of neurodevelopmental disorders (NDDs) and psychiatric disorders are considered to be multifactorial, with both genetic and environmental factors. NDDs are associated with early atypical brain development ...