Karolinska Institutet Open Archive
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Delineating cell types and toxicity in human ovaries from birth to sexual maturity
(Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2024-05-06)The ovary contains the female germ cells known as oocytes, which are essential for female fertility. The immature oocytes reside within primordial follicles in the ovarian cortex and are referred to as the ovarian reserve. ... -
Pyrocarbon in shoulder hemi arthroplasty
(Inst för kliniska vetenskaper, Danderyds sjukhus / Dept of Clinical Sciences, Danderyd Hospital, 2024-05-03)Pyrolytic carbon, or pyrocarbon (PyC), has biocompatibility, a low friction coefficient and good wear resistance, making it a material of great potential for use in orthopaedics. PyC shoulder implants have shown promising ... -
Diet, genetic susceptibility, latent autoimmune diabetes in adults, type 1 and type 2 diabetes
(Institutet för miljömedicin / Institute of Environmental Medicine, 2024-05-03)Diabetes is one of the most common chronic diseases, yet our understanding of modifiable risk factors remains incomplete. This project aimed to elucidate the role of diet in the risk of latent autoimmune diabetes in adults ... -
Hepatic diseases at the molecular level : identifying novel targets and biomarkers through transcriptomics
(Inst för mikrobiologi, tumör- och cellbiologi / Dept of Microbiology, Tumor and Cell Biology, 2024-05-03)In the last few decades, the prevalence of obesity and metabolic diseases have dramatically increased and pose a major threat to global healthcare systems. The chronic excess of carbohydrates and fat is a risk factor for ... -
Mortality prediction and equity in emergency care
(Inst för kliniska vetenskaper, Danderyds sjukhus / Dept of Clinical Sciences, Danderyd Hospital, 2024-05-03)Introduction: Emergency departments (EDs) face crowding and long patient waiting times due to resource-demand imbalances. Waiting exposes patients to sufferings and risks, such as pain, anxiety, permanent organ damage, or ...