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Pharyngeal function, airway protection and anesthetic agents
(2002-04-17)
Anesthesia related complications occur most frequently in the immediate postoperative period. The three most common conditions associated with such events are ventilatory failure, airway obstruction and aspiration. The ...
Pancreatic ductal adenocarcinoma : computed tomography for diagnosis, local staging and prediction of postoperative complications
(2015-04-30)
Pancreatic ductal adenocarcinoma (PDAC) is a disease with a dismal prognosis, being the 4th
leading cause of cancer deaths in Sweden and worldwide. The only potentially curative
therapy is surgery. Unfortunately, by the ...
Studies on ITK-SYK signaling pathways
(2013-05-24)
Chromosomal alterations are frequent causes of cancer. Until now, SYK is reported in two different chromosomal translocation events generating the ITK-SYK-fusion protein in a subset of peripheral T cell lymphomas and the ...
Regulation of NK cell activity : studies of DAP12-associated receptors in immune synapse formation and in responses to cytomegalovirus infection
(2006-10-27)
Natural killer (NK) cell effector functions are important for innate resistance against tumor cells and viral infections. NK cells display a broad range of inhibitory and activating receptors on the cell surface, which ...
Immune responses against tumors controlled by the actin cytoskeleton : lessons from primary immunodeficiencies
(2017-10-11)
The actin cytoskeleton and its regulators are vital for cellular processes such as cell motility and immune synapse formation. In this study, the aim was to dissect the role of two of those regulators, WASp and MKL1, in ...