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Immune responses against tumors controlled by the actin cytoskeleton : lessons from primary immunodeficiencies
(2017-10-11)
The actin cytoskeleton and its regulators are vital for cellular processes such as cell motility and immune synapse formation. In this study, the aim was to dissect the role of two of those regulators, WASp and MKL1, in ...
In vivo and in vitro studies of apolipoprotein CIII in diabetes
(2017-08-23)
Apolipoprotein CIII (apoCIII) is an important regulator of lipid metabolism and it is also known to have pro-inflammatory properties. From the point of view of diabetes it is interesting that both insulin deficiency and ...
In vivo regulation of pancreatic beta cell function
(2018-03-01)
Pancreatic beta cells within the islets of Langerhans contribute to the regulation of glucose homeostasis by secretion of insulin, a hormone that stimulates the uptake of glucose by liver, muscle and fat tissue. In response ...