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On the children's global assessment scale (CGAS)
(2012-02-29)
Rating scales and diagnostic instruments have become increasingly important tools in psychiatric care over the past several decades. Using these standardized tools to collect information and evaluate patients enables ...
Genome-wide study of HDACs and transcription in Schizosaccharomyces pombe
(2010-05-27)
The eukaryotic genome has to be organized to fit into the cell and this is achieved by packing of DNA into chromatin. The basic repeating structural unit of chromatin is the nucleosome, which consists of DNA wrapped around ...
Importance of pharmacogenetic and environmental factors for variation in caffeine disposition : with special emphasis on CYP1A2, CYP2A6, NAT2 and XO
(2012-03-12)
Inter-individual variation in response to drugs conveys considerable risk of either therapy failure or drug toxicity. Caffeine, as one of the most frequently used psychoactive substances in the world, is not an exception, ...
Perinatal regenerative medicine : development of autologous constructs for soft tissue defects
(2018-03-26)
Disrupted organogenesis leads to permanent malformations that may require surgical correction. Affected new-borns without spare tissue for the primary closure are dependent of other solutions. Because of the perinatal ...
HMGB1 in inflammation : secretion and function
(2008-11-07)
Rheumatoid arthritis (RA) is a chronic inflammatory disease characterised
by progressive joint destruction. The inflammatory and joint destructive
processes in RA are mediated by resident synovial cells and cells
recruited ...
Biomarkers for colon cancer : applications in human and rat studies
(2005-10-21)
Colon cancer is one of the major causes of cancer in industrialized
countries, and it is caused by a combination of hereditary, environmental
and dietary factors and lack of physical activity. Of these factors, diet
is ...
In vitro models aiming for fertility preservation
(2018-10-11)
Fertility preservation is considered a great hope to people suffering from infertility as a consequence of developmental or genetic cause, a disease itself or its treatments sequelae. In vitro models are fundamental to ...
Treatment of displaced femoral neck fractures in the elderly
(2017-11-23)
Femoral neck fracture (FNF) in elderly patients is a common cause of suffering and premature death in individuals with osteoporotic bones. This fracture type is more common in women after menopause, and the associated ...
Targeting DNA repair pathways for cancer therapy
(2017-01-20)
Accumulation of genomic mutations is the consequence of failure in DNA repair as well as increased exposure to endogenous/environmental mutagens. DNA repair pathways safeguard the human genome from such mutagens, and thereby ...
Local infiltration analgesia in knee and hip arthroplasty efficacy and safety
(2014-05-02)
Local infiltration analgesia (LIA) is a new multimodal wound infiltration method. It has attracted growing interest in recent years and is widely used all over the world for treating postoperative pain after knee and hip ...