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Medical interventions and gastric cancer risk : an observational approach
(2004-05-14)
characteristics
of the relationship between H. pylori infection and gastric cancer, and
to assess the risk of gastric cancer following antibiotic and
anti-inflammatory treatments.
In a previous cohort study of 39,000 hip replacement patients, identified...
Studies of targeted therapy in breast cancer using trastuzumab : HER2 testing and trastuzumab treatment, clinical and economic evaluation
(2011-09-22)
The incidence in breast cancer has more than tripled in Sweden since the 1960-ies. During the same time period the 5-year survival rate has increase from around 65% to almost 90%. The survival increase is mainly related ...
Genome-wide study of HDACs and transcription in Schizosaccharomyces pombe
(2010-05-27)
The eukaryotic genome has to be organized to fit into the cell and this is achieved by packing of DNA into chromatin. The basic repeating structural unit of chromatin is the nucleosome, which consists of DNA wrapped around ...
Drug and alcohol induced hepatotoxicity
(2008-05-23)
. Pathological changes were significantly increased after EtOH treatment, and principal component analysis showed that among parameters influencing total pathology score, para-nitrophenol activity mirroring CYP2E1 activity, had the highest impact. Analysis of 39,000...
Interferons in antiviral defense and autoimmunity : focus on type 1 diabetes
(2008-01-04)
Type 1 diabetes (T1D) is a disease characterized by the loss of insulin
producing beta-cells in the pancreatic islets of Langerhans. Interferons
(IFNs), produced by immune cells and infected parenchymal cells, may ...
Immune responses against Mycobacterium tuberculosis targets associated to latent and active tuberculosis infection
(2014-09-01)
Background: Tuberculosis is a worldwide problem particularly in developing countries. Different clinical outcomes, such as the asymptomatic phase during infection or the symptomatic stage during active disease leads to ...
HIV-1 drug resistance and molecular epidemiology in Honduras
(2011-12-28)
The high genetic diversity and rapid evolution of HIV-1 poses a challenge to the worldwide prevention and treatment programs. Effective antiretroviral treatment has significantly improved the quality of life for HIV-infected ...
HIV trends, risk behaviours, social structural barriers and retention in HIV care among key populations in Nepal and the Asia-Pacific region
(2017-05-09)
Background: The HIV epidemic in the Asia-Pacific region is characterised by a number of concentrated, and in some geographical areas, growing epidemics, particularly among key populations [men who have sex with men (MSM), ...
Molecular characterization of Mycobacterium tuberculosis complex isolates from Sweden
(2010-04-21)
Tuberculosis (TB), caused by the Mycobacterium tuberculosis complex
(MTC), is a serious infection in man and animals. According to the World
Health Organisation (WHO), about one third of the world´s population is
infected ...
Development of novel DNA vaccine and immunotherapeutic approaches
(2009-08-06)
Many potential DNA vaccination and immunotherapeutic strategies has been explored in both animal models and human settings in recent years. However, the failure of efficient and safe method development suggests that it is ...