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Hemodynamic optimization in critically ill patients
(2024-02-23)
Background: Intravenous fluids are one of the most common treatments in the health care setting and are usually given in response to hemodynamic instability or shock. However, this rests on the assumption that the cause ...
Serodiagnostics of schistosomiasis using keyhole limpet hemocyanin (KLH) as antigen
(2006-04-20)
The diagnostics of invasive helminth infections is often indirect and based on antibody detection in serum specimens from infected individuals. This is the case in schistosomiasis (bilharzia) where no excreted eggs can be ...
Regulation of bacterial adaptive behavior by the second messenger cyclic-di-GMP and host components
(2015-01-15)
To optimize survival and growth, bacteria have evolved adaptive behaviors that respond to relevant environmental signals. A switch from the motile to the sessile lifestyle is probably the most ancient behavioral transition ...
Comorbidity in risk and outcome of hematological malignancies
(2016-03-01)
Hematological malignancies are a group of neoplasms that originate from the bone marrow or lymphatic tissues representing close to 10% of the overall cancer burden in the world. Clinical course, prognosis and survival ...
Risk factors for criminal offending among men with schizophrenia
(2006-02-15)
Background: There is consistent evidence for an association between schizophrenia and criminal offending. With better knowledge of the relation between schizophrenia and criminal offending, better and more cost-effective ...
Novel pathways regulating glucose and lipid metabolism in human skeletal muscle
(2009-04-06)
The utilization of glucose and lipids as energy substrates in skeletal
muscle is strictly regulated. As skeletal muscle is the body s chief
consumer of glucose and lipids, it plays a critical role in the
maintenance of ...
Recessive parkinsonism, mitochondria and translational regulation
(2008-09-05)
Three genes are known to cause recessive forms of Parkinson disease (PD) in humans: parkin, PINK1 and DJ-1. Of these, the rarest is DJ-1; less than fifty known cases worldwide are due to mutations in DJ-1. Though rare, ...
Repressing the hedgehog signalling pathway
(2007-11-28)
The Hedgehog (Hh) signalling pathway is essential for metazoan development and aberrant activation of the pathway is found in tumours. Mutations in Hh pathway components are found in several tumour types, including basal ...
Neonatal respiratory control : inspiration, inflammation and the prostaglandin E2 pathway
(2014-10-22)
Immature or deficient autonomic control is a common problem in infants born at a premature age, and is of central importance in apneas. The pre- and perinatal development of the brainstem neural circuits that control ...
Provoked vestibulodynia : studies on pain genetics and pain co-morbidity
(2014-01-15)
Objective: The purpose of this thesis was to investigate a possible genetic predisposition for developing provoked vestibulodynia (PVD), focusing on previously defined single nucleotide polymorphisms (SNPs) in three genes ...