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Comorbidity in risk and outcome of hematological malignancies
(2016-03-01)
Hematological malignancies are a group of neoplasms that originate from the bone marrow or lymphatic tissues representing close to 10% of the overall cancer burden in the world. Clinical course, prognosis and survival ...
Studies of nuclear encoded mitochondrial proteins in metabolism
(2021-11-19)
Mitochondrial function is vital for human health. Inherited genetic disease can cause mitochondrial DNA (mtDNA) deficiency, disorders with generally poor prognosis. The majority of the genesinvolved in keeping a normal ...
Understanding the heterogeneity of the hematopoietic stem cells
(2022-11-25)
The hematopoietic system is replenished and maintained throughout life by rare hematopoietic stem cells (HSCs) that reside in the bone marrow (BM) of adult mammals. Over the last 20 years, the advancement in the field lead ...