Search
Now showing items 1-5 of 5
Integrative omics data analysis to discover novel signatures in complex diseases
(2023-03-09)
Apart from diseases caused by the defect of a single gene, most diseases are highly complex and are usually caused by a combination of biological and environmental factors. In the biological context, cellular processes are ...
Cytokine-modulated dendritic cell immunotherapy in autoimmune diseases
(2005-01-14)
Autoimmunity is the result of failure of self-tolerance processes. When the immune system fails to differentiate self from foreign, the effector mechanisms are directed towards the individual s own tissues, and pathological ...
Prosthetic aortic heart valves
(2018-08-21)
Background: Aortic valve replacement (AVR) can be performed with different types of valve prostheses. There is no perfect aortic valve prosthesis, and the prosthetic choice for each patient requires careful consideration. ...
Neutrophil interactions with Streptococcus pyogenes and Staphylococcus aureus
(2017-04-03)
Streptococcus pyogenes and Staphylococcus aureus are Gram-positive bacteria that share many features, including clinical presentations and pathogenic mechanisms, and yet, they still have unique properties. They both cause ...
DNA topoisomerases and nucleosome dynamics in fission yeast
(2015-05-12)
The organization of DNA and associated proteins into chromatin allows for compaction and protection of large eukaryotic genomes. However, it also poses a challenge to fundamental cellular processes such as DNA replication, ...