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Neutrophil interactions with Streptococcus pyogenes and Staphylococcus aureus
(2017-04-03)
Streptococcus pyogenes and Staphylococcus aureus are Gram-positive bacteria that share many features, including clinical presentations and pathogenic mechanisms, and yet, they still have unique properties. They both cause ...
DNA repair by HDR in experimental tumorigenesis
(2008-05-15)
The aim of this thesis was to further understand how defects in the homology-directed repair (HDR) pathway affect tumor formation and development. To study proteins involved in HDR is challenging since most of its members ...
Studies on the gamma-secretase complex and processing of the Alzheimer's disease-associated amyloid precursor protein
(2004-03-26)
Alzheimer's disease (AD) is a devastating neurodegenerative disorder that
causes the most common form of dementia. Pathological lesions, such as
plaques consisting of the amyloid beta-peptide (Ab), are found in the
brains ...
Immune mechanisms in atherosclerotic vascular disease
(2002-05-14)
Atherosclerosis has been categorized as an inflammatory disorder, with similar chronic inflammatory conditions found in rheumatoid arthritis. It entails an unregulated accumulation of lipids in the vessel wall, which leads ...
Prostate cancer testing in Sweden : the interplay between cost and effectiveness
(2022-11-16)
As a major cause of male deaths in Sweden, prostate cancer constitutes an essential public health issue to the society. Early detection through an organised testing program with the prostate-specific antigen (PSA) test and ...