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Studies on myeloid cell functions in periodontitis
(2020-08-05)
Periodontitis (PD) is a chronic inflammatory disease characterized by destruction of the tooth supporting tissues; gingiva, periodontal ligament, and alveolar bone. Myeloid cells, including monocytes and macrophages, play ...
Cervical intraepithelial neoplasia in migrant women living with HIV
(2018-10-19)
The aim of this thesis was to study high-grade cervical intraepithelial neoplasia (CIN) in women
living with HIV (WLWH) in Sweden compared with HIV-negative women (HNW) of the same
region of birth.
In Paper I ...
Human cytomegalovirus in congenital infections and embryonal malignancies of the nervous system
(2009-10-02)
Cytomegalovirus (CMV) is a herpesvirus that may cause severe or even fatal disease in immunocompromised patients as well as severe developmental disturbances in foetuses infected in utero. In contrast, only mild symptoms ...
Diagnostic tests for adiposity and metabolic risk factors in adolescence : results from the Stockholm weight development study (SWEDES)
(2005-03-25)
Background: Despite growing concern about the development of pediatric
obesity, there is still controversy about its classification.
International classification systems have been proposed and national
systems are in ...
Role of membrane associated molecules in liver fibrosis
(2008-03-07)
The aim of the study was to evaluate the role of membrane associated proteins in tissue formation and remodeling, in normal embryogenesis and in liver disease. Molecules associated with cellular membranes provide a ...
Improving treatment outcomes for patients with pulmonary tuberculosis in Tanzania : host and pathogen factors
(2017-11-08)
Tuberculosis (TB) causes more than 1.2 million deaths each year globally. Yet, survivors of tuberculosis are left with long term sequelae of chronic inflammatory responses with consequent reduced quality of life. Biomarkers ...
Oral mucositis and periodontal disease in patients with primary or acquired immunodeficiencies
(2013-09-11)
The infection and inflammation in the oral cavity are commonly related to the skewed interaction between host immunity and inhabiting microorganisms. Both primary and acquired immunodeficiency conditions are frequently ...
Epiphora : impact on vision, outcome of lacrimal surgery and investigations with ultra-high-frequency ultrasound
(2021-04-08)
Epiphora is a common condition that often receives little attention. Excessive tear production creates an irregular and ever-changing ocular surface, affecting refraction and reducing vision. However, in a standard test ...
Detecting novel effects of exercise or AMPK activation in human skeletal muscle
(2018-04-24)
Cardiovascular and metabolic disorders are among the main causes of death today. Regular exercise can prevent and treat these chronic diseases. A molecule at the center of exercise adaptations in skeletal muscle is adenosine ...
Human muscle response to sprint exercise and nutrient supply with focus on factors related to protein metabolism
(2016-12-21)
The overall aim of the present thesis was to study the muscular response to repeated bouts of 30-s sprint exercise. This type of exercise gives rise to a profound metabolic perturbation that might counteract an exercise-induced ...