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Role of membrane associated molecules in liver fibrosis
(2008-03-07)
The aim of the study was to evaluate the role of membrane associated proteins in tissue formation and remodeling, in normal embryogenesis and in liver disease. Molecules associated with cellular membranes provide a ...
T-cell specificity and regulation in atherosclerosis
(2015-12-14)
Cardiovascular disease is the main cause of death in the world. The underlying cause in most cases is atherosclerosis, a chronic inflammatory disease. Subendothelial retention of lipoproteins triggers monocyte-derived ...
Natural killer cells in cancer : studies on migration and cytotoxicity
(2014-05-08)
The role of natural killer (NK) cells in cancer development has been studied extensively over the last four decades and the increasing knowledge on NK cell regulation has improved both safety and efficacy of treatment. ...
Studies of stem cell and adhesion proteins in breast cancer
(2014-10-06)
Breast cancer is the commonest cancer and second leading cause of cancer death in women. It has been shown that breast cancer tumorigenic/stem cell like cells are CD24-/low CD44+EpCAM+. These cells constitute less than 5% ...
Tall stature : morbidity, mortality and treatment outcomes
(2016-01-15)
Tall stature is usually constitutional. In some cases excessive growth is caused by early puberty and in others by growth disorders such as Marfan syndrome or pituitary gigantism. Some individuals experience a substantial ...
Eliminating guesswork : an exploration of the role of predictive modelling in care management for patients with multimorbidities
(2022-05-20)
Introduction: Patients with multiple chronic conditions of diabetes, cardiovascular and kidney diseases are one of the most complex group of patients and high consumers of care. Multidisciplinary integrated care delivery ...
Acquired brain injury and evaluation of intensive training of attention in early neurorehabilitation : statistical evaluation and qualitative perspectives
(2017-05-11)
Attention dysfunction is a cardinal symptom after an acquired brain injury (ABI) sometimes leading to life-long consequences that affect learning skills, daily functioning and social and emotional life. Attention may be ...
Psychomotor disturbances in bipolar disorder : investigations using structural and functional neuroimaging
(2013-09-11)
Psychomotor disturbances in bipolar disorder are an expression of alterations in volition, cognition, emotion and motor control. While psychomotor disturbances remain a classic hallmark of severe mood disorders, there is ...
Determinants and influence of mammographic features on breast cancer risk
(2020-11-16)
Mammographic density and mammographic microcalcifications are the key imaging features in mammography examination. Mammographic density is known as a strong risk factor for breast cancer and is the radiographic appearance ...