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A study of two major challenges in prostate cancer : effective chemo-prevention and overcoming resistance to hormonal and chemotherapy
(2018-06-29)
For men, over the course of a lifetime the risk of developing prostate cancer is 1 in 9. Both the illness itself and treatment affect quality of life in multiple aspects, including urinary problems, pain, and sexual ...
Peripheral nerve glia as multipotent progenitors in craniofacial development
(2014-12-22)
Craniofacial development is complex. Numerous populations of progenitor cells coordinate
activities to produce an array of highly integrated tissues inside the developing head.
However, it is not clear how some key ...
Molecular genetic studies of psoriasis susceptibility in 6p21.3
(2005-02-18)
Psoriasis is a common and chronic skin disease with multifactorial background. It affects approximately 2% of the Swedish population and is characterized by inflammatory and scaly lesions. The aetiology of psoriasis is not ...
Functional gastrointestinal disorders : co-morbidity and non-somatic aspects
(2008-05-19)
Aims of the thesis: The first aim, (Study I) of this thesis was to
compare co-morbidity of the reported symptoms and its relation to
healthcare seeking behaviour among non-patients who had persistent
functional ...
Severe COVID-19 and routine biomarker patterns
(2023-10-10)
In acute infectious diseases, the composition of the blood changes. That includes
proteins, blood cells and smaller solutes. Routine blood tests have a fundamental role in
the diagnosis and follow-up of patients with ...
Role of IL-7 in immune activation during HIV-1 infection
(2011-08-02)
Viral replication, lymphopenia and microbial translocation at the mucosal surfaces lead to a chronic state of immune activation during HIV-1 infection. Chronic immune activation is believed to impact on the functionality ...
Regulation of neurogenesis in the vertebrate CNS
(2008-02-22)
During development, neurons are generated from self-renewing progenitor cells in the ventricular zone of the neural tube. Proneural bHLH proteins are involved in the regulation of neurogenesis and can direct the exit of ...
Respiratory mononuclear phagocytes during steady state and sarcoidosis
(2020-08-25)
Each day, our lungs inhale thousands of liters of air containing not only essential oxygen but also smoke particles, dust, allergens, and potentially dangerous pathogens. In order to tolerate harmless antigens and initiate ...
Interleukin 15 throughout murine natural killer cell biology
(2020-07-31)
Natural killer (NK) cells are innate immune cells that mount responses against virally infected, transformed and allogeneic transplanted cells. Equipped with cytolytic molecules and death receptors, NK cells mediate ...
Acquired brain injury and evaluation of intensive training of attention in early neurorehabilitation : statistical evaluation and qualitative perspectives
(2017-05-11)
Attention dysfunction is a cardinal symptom after an acquired brain injury (ABI) sometimes leading to life-long consequences that affect learning skills, daily functioning and social and emotional life. Attention may be ...