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Molecular genetic studies of psoriasis susceptibility in 6p21.3
(2005-02-18)
Psoriasis is a common and chronic skin disease with multifactorial background. It affects approximately 2% of the Swedish population and is characterized by inflammatory and scaly lesions. The aetiology of psoriasis is not ...
A study of two major challenges in prostate cancer : effective chemo-prevention and overcoming resistance to hormonal and chemotherapy
(2018-06-29)
For men, over the course of a lifetime the risk of developing prostate cancer is 1 in 9. Both the illness itself and treatment affect quality of life in multiple aspects, including urinary problems, pain, and sexual ...
Diagnostic and pathophysiological aspects of Capnocytophaga canimorsus infections
(2016-09-21)
Dog- and cat-related wound-infections in humans are common. Capnocytophaga canimorsus and Capnocytophaga cynodegmi can be transmitted from dogs and cats to humans via bites or scratches. C. canimorsus is considered to be ...
Ionic modulators of stem cell state
(2016-04-27)
Tissue generation during development and maintenance throughout life relies on the proliferation and sequential specification of a group of cells. Stem cells are defined by the properties of self-renewal (division to produce ...
Molecular and clinical studies of intestinal malrotation
(2022-04-13)
Intestinal malrotation (IM) can present as a potentially life-threatening condition with midgut volvulus and need of immediate surgery, but also as a chronic condition with long-lasting symptoms. It is a well-known neonatal ...
Bacterial communities and antibiotic resistance in human-impacted water environments
(2019-11-07)
From a One-Health concept the health of humans, animals and the environment is interconnected and what happens to one of the domains will affect the other two simultaneously. This concept can be applied not only to the ...
Modulating the activity of OGG1 using small molecules to target the oxidative DNA damage response in cancer and inflammation
(2021-10-05)
The production of reactive oxygen species (ROS) is increased in several pathological conditions including cancer and inflammation. Multiple lines of evidence suggest that ROS are involved in signaling events that promote ...