Search
Now showing items 1-10 of 12
Cognitive mechanisms in pain processing : assessed with functional imaging methods
(2002-08-09)
The intensity and unpleasantness of a painful experience is often described as correlating well with the degree of noxious stimulation. However, the perception of pain is not a linear phenomenon, reflecting the signal from ...
The role of the tumor suppressor gene, FBW7, and mechanisms of its inactivation in cancer
(2011-05-17)
The F-box protein FBW7 is a tumor suppressor and SCF ubiquitin ligase targeting several key oncoproteins for proteasomal degradation. In this thesis we addressed whether the FBW7 gene is inactivated by mutations in various ...
Molecular characterization of Mycobacterium tuberculosis complex from Kampala, Uganda
(2008-11-27)
Uganda is one of the countries with the highest burden of tuberculosis (TB) in Sub-Saharan Africa, ranked 16th among the 22 high-burden countries in the world. Poor peri-urban areas of developing countries with inadequate ...
Cyclophosphamide and treosulfan in the conditioning regimen prior to allogeneic stem cell transplantation
(2011-05-25)
Allogeneic stem cell transplantation (SCT) is a curative treatment for malignant and non-malignant diseases. However, transplantation related morbidity and mortality are major drawbacks affecting the survival and life ...
Epidemiological aspects on pain in whiplash-associated disorders
(2007-03-23)
Introduction: Whiplash-associated disorders (WAD) are common after car collisions. Little is known about risk factors for onset of the injury or about factors influencing the recovery.
Objective: The general objective ...
Bicuspid aortic valve-associated aortopathy unraveling the molecular signature
(2013-05-22)
Patients with bicuspid aortic valve (BAV) have an increased risk of developing ascending aortic aneurysm compared with individuals with a tricuspid aortic valve (TAV). A crucial factor involved in vascular remodeling during ...
Neck pain : factors of importance for the risk and prognosis
(2014-08-19)
Introduction: Considering the recurring nature of neck pain, and that it is a big societal as well as individual burden, it is of great importance to increase the knowledge about what factors that affect the risk and ...
Haemostatic and inflammatory alterations in hypertension and hyperlipidaemia, and the impact of angiotensin II
(2017-08-29)
The process of atherosclerosis is multifactorial, and endothelial dysfunction is considered to precede atherosclerosis. Angiotensin (Ang) II, the main effector of renin-angiotensinaldosterone system (RAAS), is implicated ...
On the function endogenous pain controlling systems in healthy subjects and patients with peripheral or central neuropathic pain
(2008-09-05)
Introduction and aim: Activity in the nociceptive system is modulated by descending inhibitory and facilitatory supraspinal endogenous control. Altered balance between inhibition and facilitation has been suggested to at ...
Endocrine signaling and molecular aberrations in primary hyperparathyroidism
(2013-09-27)
Primary hyperparathyroidism is a common endocrine disorder, characterized by an inappropriate increase in serum parathyroid hormone (PTH) levels. It is most often caused by a single benign parathyroid tumor. The elevated ...