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Cyclophosphamide and treosulfan in the conditioning regimen prior to allogeneic stem cell transplantation
(2011-05-25)
Allogeneic stem cell transplantation (SCT) is a curative treatment for malignant and non-malignant diseases. However, transplantation related morbidity and mortality are major drawbacks affecting the survival and life ...
The Alzheimer’s disease related gamma-secretase complex : localization and novel interacting proteins
(2010-05-07)
Alzheimer’s disease (AD) is caused by synaptic and neuronal loss in the
brain that eventually results in cognitive decline. Characteristic
hallmarks of AD are senile plaques containing the amyloid beta-peptide
(Abeta) ...
Tissue distribution studies and risk assessment of perfluoroalkylated and polyfluoroalkylated substances (PFASs)
(2013-05-15)
Perfluoroalkylated and polyfluoroalkylated substances (PFASs) represent a large class of man-made chemicals. These substances have emerged as environmental contaminants due to their extraordinary resistance to degradation, ...
High antibiotic use and resistance among children under five : acute respiratory infections : knowledge and behaviour of caregivers and healthcare providers in Vietnam
(2010-04-30)
Background: Increased bacterial resistance is threatening the therapeutic
effectiveness of antibiotics. High level of antibiotic use is probably
the main factor driving the emergence of resistance. Streptococcus
pneumoniae ...
DNA topoisomerases and nucleosome dynamics in fission yeast
(2015-05-12)
The organization of DNA and associated proteins into chromatin allows for compaction and protection of large eukaryotic genomes. However, it also poses a challenge to fundamental cellular processes such as DNA replication, ...