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Immunoregulatory effects of placenta-derived decidual stromal cells
(2016-01-08)
Decidual stromal cells (DSCs) play a pivotal role in feto-maternal tolerance to prevent rejection of the fetus during pregnancy. This provides a rationale for immunomodulatory stromal cells from the placenta being isolated ...
Study of neurodegenerative diseases with novel MRI techniques
(2015-05-19)
Neurodegenerative diseases are a heterogeneous group of disorders that are
characterized by the progressive degeneration of structure and function of the nervous
system. They include diseases such as Alzheimer’s disease ...
Alzheimer disease : studies on Abeta and gamma-secretase in human brain
(2010-01-15)
Alzheimer disease (AD) is a devastating neurodegenerative disorder and
the most prevalent form of dementia. One hallmark of the disease is the
extracellular deposition of amyloid beta-peptide (Abeta) into senile
plaques ...
Na,K-ATPase as signaling transducer
(2007-11-27)
It is now generally agreed that Na,K-ATPase (NKA), in addition to its
role in the maintenance of Na+ and K+ gradients across the cell membrane,
is a signal transducer. Our group has identified a novel signaling
pathway ...
Sarcopenia
(2005-11-21)
Sarcopenia (Greek; sarcos: flesh, and penia: poverty) is the pronounced muscle loss that affects the aging population. Sareopenia of the leg muscles results in loss of independence and increased morbidity in the elderly. ...
Studies on Labisia pumila var. alata extract with phytoestrogenic effects : impact on biological activities and gene expression
(2010-10-27)
In Malaysia, Labisia pumila var. alata (LPva) has been used by women for generations.
Traditionally, the plant is boiled, either alone or in decoction with other herbs. It is claimed to
have health benefits such as to ...
Musculoskeletal injuries and generalized joint laxity in ballet dancers
(2012-09-13)
Aims: To examine the incidence and type of musculoskeletal injuries in classical ballet dancers, to analyse these injuries in relation to absence from performance, and to identify dancers at risk of frequent injuries in a ...
Origin of intraradicular infection with Enterococcus faecalis in endodontically treated teeth
(2015-05-13)
The reported prevalence of Enterococcus faecalis, both a commensal of the gastro-intestinal tract and a common nosocomial pathogen, ranges from 24% to 77% in post-treatment root canal infections. To date it has not been ...
Establishment and applications of a multiple sclerosis biobank : analysis of biomarkers and therapeutic complications in MS
(2010-02-05)
Biomarkers for disease activity and prognosis in multiple sclerosis (MS)
are lacking. We established a MS biobank consisting of paired
cerebrospinal fluid samples (CSF) and peripheral blood samples from MS
patients and ...
Characterisation of CD8 T cells in mucosa associated lymphoid tissue : implications for immune control of HIV-1 infection
(2006-02-24)
The role of CD8 T cells has been implicated in the partial immune control of HIV-1 infection. Ultimately these cells fail to control the infection and immune deficiency ensues in the absence of antiretroviral therapy. A ...