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Assessment of pancreatic islet cell function and survival
(2015-05-22)
Function and survival of pancreatic islet insulin-producing beta-cells (β-cells) and glucagonproducing
alpha-cells (α-cells) were studied, and methods for this purpose were developed or
refined.
Dynamic control ...
Characterization of ERp29 : a novel secretion factor of endoplasmic reticulum
(2005-04-29)
ERp29 is a ubiquitously expressed endoplasmic reticulum protein strongly
conserved in mammalian species. The N-terminal domain of ERp29 is similar
to the thioredoxin domain of protein disulfide isomerase (PDI) lacking
however ...
Characterisation of human fetal mesenchymal stem cells
(2004-11-26)
Mesenchymal stem cells (MSCs) are present in various tissues of fetal and adult origin. I isolated and expanded MSCs from human fetal 1st trimester livers and observed that they have a shorter cell doubling time compared ...
Antiretroviral drug resistant HIV-1 in women and children living in Honduras
(2013-02-15)
Antiretroviral therapy (ART) in HIV infected pregnant women contributes to the prevention of HIV transmission to the newborn. However, as ART can also induce HIV drug resistance during suboptimal levels of virological ...
New approaches to treat women’s urogenital problems
(2014-11-10)
Women’s urogenital problems adversely affect their quality of life. In this thesis, I address tw oof such urogenital problems: namely, postmenopausal vaginal atrophy (VA) and stress urinary incontinence (SUI). In the first ...
Reconstruction of vocal fold scarring with mesenchymal stromal cell therapy
(2019-10-24)
Tissue injury/scarring of the vocal folds (VFs) can be caused by various factors including external trauma, cancer treatment or inflammation, leading to damage within the vibrating layers and a decrease in viscoelastic ...
Immunoregulatory effects of placenta-derived decidual stromal cells
(2016-01-08)
Decidual stromal cells (DSCs) play a pivotal role in feto-maternal tolerance to prevent rejection of the fetus during pregnancy. This provides a rationale for immunomodulatory stromal cells from the placenta being isolated ...
Healthcare financing challenges and opportunities to achieving universal health coverage in the low- and middle-income country context
(2020-02-05)
Background: In Bangladesh, on an average 62% of total healthcare spending was borne by households through out-of-pocket (OOP) payments annually during 2000- 2015. Because of such high OOP payments, a sizeable proportion ...