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Motivating clinical treatment of obesity : methods, education, supervision and outcome
(2004-11-05)
Obesity has become an important health problem worldwide. It increases
the medical risks and affects daily living. Environmental factors such as
diet and sedentary lifestyle are likely to be the cause. In Sweden, the
number ...
Truncation and missing family links in population-based registers
(2008-03-07)
Studies of familial aggregation of disease routinely use linked
population registers to construct retrospective cohorts. Although such
resources have provided numerous estimates of familial risk, little is
known regarding ...
Contracting muscle for regeneration : myogenic dedifferentiation in limb progenitor cell formation
(2008-01-04)
The urodele amphibians, such as newts and axolotls, are unique among
vertebrates since they regenerate their limbs, tail, jaws and part of
their heart and CNS as adults. After amputation of a newt limb,
regeneration ...
Expression and function of the small immune adaptor protein SAP
(2006-11-27)
The Epstein-Barr virus (EBV) carrier state is widespread in humans. Primary infection can cause infectious mononucleosis (IM) that presents with variable clinical severity, but almost always subsides. For 50% of boys with ...
Leisure activities at old age and their influence on dementia development
(2009-04-20)
This thesis aims to describe the participation in leisure activities of elderly subjects and to detect their possible effect, if any, on the development of dementia. The data were derived from the Kungsholmen Project, which ...
Plasticity of salamander skeletal muscle cells
(2012-03-06)
Regeneration is unevenly spread throughout the animal kingdom. Some of the invertebrates have a very high regenerative capacity but the capacity to replace lost or damaged tissues in mammals is limited. Among the vertebrates, ...
Two novel combination therapies of glioblastoma multiforme from a Cx43 perspective : studies of in vitro models
(2008-03-28)
The group of patients suffering from the malignant brain tumour
glioblastoma multiforme (GBM) have a median survival of only about one
year. Thus, new treatment strategies are urgently needed.
Gap junctions are ...
Studies on the phenotype and function of osteoclasts using osteopetrotic and rachitic animal models
(2007-09-07)
Osteoclasts are multinucleated bone-resorbing cells that have been
implicated in a variety of skeletal diseases e.g. osteoporosis,
rheumatoid arthritis and skeletal metastasis. Under physiological
conditions, the osteoclast ...
Perinatal and familial risk factors of youth suicidal behaviour
(2005-10-28)
Completed suicide constitutes one of the leading causes of death in adolescents and young adults. Youth suicide attempt often precedes completed suicide and represents in itself a considerable public health problem in ...
Elucidation of pro-apoptotic signaling induced by cisplatin
(2003-02-07)
A major clinical problem regarding treatment of malignant tumors with anticancer drugs is inherent or acquired resistance to therapy. One factor contributing to drug resistance of cancer cells is failure to undergo apoptosis. ...