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A reason to be bitter : cassava classification from the farmers' perspective
(2001-11-16)
Ethnographers report from both South America and Africa that cassava
farmers classify cultivars as belonging to either of two groups, "bitter"
or "sweet", and that farmers prefer to grow "bitter" cultivars as the
staple ...
Neuropeptide Y (NPY) and glutamate transporter (GLAST) in behavioral models of psychiatric disorders
(2008-12-26)
For many psychiatric disorders there are still unmet needs for treatment. Using genetically modified mice provide means to study the systems that underlie these disorders as well as identifying potential novel targets for ...
HLA predisposition to human papillomavirus induced cervical neoplasia : population based studies from the Västerbotten county in northern Sweden
(2001-08-08)
Infection with human papillomaviruses (HPV) types 16 and 18 is the major
cause of cervical neoplasia. Although a high proportion of cervical
cancers (CXCA) harbor HPV genomes, only a small number of women infected
with ...
Tumor microenvironment derived biomarkers in renal cell cancer
(2017-11-16)
Renal cell carcinoma (RCC) is the 13th most common malignancy worldwide, and constitutes around 2% of all malignant tumors. The entity renal cell carcinoma comprises a heterogenous group of malignant tumors that originates ...
Neurorestorative strategies involving neurogenesis, neuronal precursors and stem cells in animal models of Parkinson's disease
(2009-10-08)
The general aims of the thesis is to provide evidence for neurogenesis in the adult substantia nigra pars compacta (SNpc), where the dopamine-producing neurons lost in Parkinson's disease (PD) reside; to optimize methods ...
On antidepressant effects of running and SSRI : focus on hippocampus and striatal dopamine pathways
(2007-05-25)
Considering the heterogeneous character of depression, it seems likely
that many brain regions are involved mediating the diverse symptoms of
depression. For example, the mesolimbic DA system has a central function
for ...
Significance of adipose tissue characteristics for development of metabolic complications in obesity
(2014-11-14)
Background: Obesity is closely related to development of insulin resistance and dyslipidemia. Intrinsic properties of adipose tissue are also of great importance for obesity related comorbidity. The aim of this thesis was ...
Experimental studies of N-methyl-D-aspartate receptor NR3 subunits
(2008-04-25)
This thesis focuses on the NR3A and NR3B subunits of the excitatory
glutamate receptor N-methyl-D-aspartate (NMDA). Functional NMDA receptors
are believed to be tetrameric complexes with combinations of NR1 and NR2
subunits, ...
The role of EBNA binding proteins in cell transformation
(2013-05-06)
Epstein-Barr virus (EBV) infects majority of the human population and maintains sub-clinical infection. However, under certain conditions it is associated with several B-cell malignancies, such as Burkitt lymphoma, Hodgkin’s ...
Formation of the inhibitory KIR repertoire in human natural killer cells
(2012-01-23)
Natural killer (NK) cells are lymphocytes of the innate immune system that are able to secrete cytokines and detect virus infected and transformed cells. Contrary to T cells, NK cells recognize targets that lack expression ...