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Neurorestorative strategies involving neurogenesis, neuronal precursors and stem cells in animal models of Parkinson's disease
(2009-10-08)
The general aims of the thesis is to provide evidence for neurogenesis in the adult substantia nigra pars compacta (SNpc), where the dopamine-producing neurons lost in Parkinson's disease (PD) reside; to optimize methods ...
Expression and function of thyroid hormone receptor alpha 1 in the brain
(2011-01-10)
Thyroid hormone is fundamentally important for development and maintenance of adult brain functions and maternal hypothyroxinemia during pregnancy can lead to a severe mental retardation known as endemic cretinism. The ...
From molecule to neuron : thyroid hormone action in the brain
(2015-10-16)
The importance of thyroid hormone (TH) for mental health has been known for decades. With the identification of the thyroid hormone receptors α and β (TRα, TRβ), TR dependent mechanisms involved in brain development were ...
Surgical reconstruction of functional and anatomical defects in the diaphragmatic hiatus
(2022-05-10)
Gastroesophageal reflux disease (GERD) is characterized mainly by heartburn and acid regurgitation but in the more severe forms even organic manifestations can occur. Proton pump inhibitors (PPIs) is the main medical ...