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Innate immunity in atherosclerosis : the role of pattern recognition receptors
(2014-10-15)
The pathogenesis of atherosclerosis is greatly influenced by the activities of both innate and adaptive immunity. Danger signals such as cholesterol crystals, oxidized LDL, and modified phospholipids may trigger sterile ...
Protein expression in prostate cancer
(2006-01-06)
The molecular pathology of prostate cancer (PCa) is complex and the pathways and the acquired molecular defects responsible for PCa initiation, development and progression are still largely unknown. Tumors of the prostate ...
A study of the transition from premalignancy to clinical prostate cancer
(2005-09-16)
Prostate cancer remains the most commonly diagnosed life-threatening malignancy and the second leading cause of death from cancer in men. However, little is known about molecular mechanisms that underline its initiation ...
Analysis of functional genetic polymorphisms in prostate cancer and type 2 diabetes : mucin 1 and growth hormone receptor
(2008-10-03)
Prostate cancer and type 2 diabetes are complex diseases, the genetic and
environmental basis of which are not well established. Epidimiology
suggests a link between the two diseases, with type 2 diabetes redusing
the ...