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Using enriched quality register data for health care evaluation : examples from rheumatoid arthritis
(2014-09-24)
Swedish registers have for decades successfully been used for medica research, enabling long-term follow-up of large patient cohorts using observational designs. With a tax funded health care system and the use of a personal ...
Toll-like receptor-induced cytokine secretion by human monocytes in healthy donors and septic patients assessed at the single cell level
(2013-08-23)
Following the ligation of Toll-like receptors (TLRs) by bacterial-derived signature molecules, innate immune cells such as monocytes, macrophages and neutrophils initiate the inflammatory process by secreting chemokines ...
Pregnancy in Ro/SSA positive women
(2013-05-14)
Congenital heart block (CHB) may develop in the fetus during pregnancy in Ro/SSA positive women. It is a rare but life-threatening disease and the most serious manifestation of neonatal lupus erythematosus (NLE). The ...
Antimicrobial peptides and eicosanoids : roles and interactions in inflammation and host defense
(2017-04-05)
Antimicrobial peptides (AMPs) have a broad spectrum of activities and exert their functions by both direct killing of microbes through the interaction with the microbial membrane, and modulation of innate and adaptive ...
Immune evasion and dissemination of Toxoplasma gondii
(2009-08-24)
Toxoplasma gondii is an obligate intracellular protozoan parasite which propagates in a complex life cycle where infection of Felidae family-members (Cats) results in sexual recombination whereas all other warm-blooded ...
Causes and mechanisms of an adverse outcome in patients with glucose abnormalities and cardiovascular disease : epidemiological and biochemical analyses
(2016-10-26)
Background: Diabetes and previously undetected glucose abnormalities are common in patients with acute myocardial infarction (AMI). It is well established that patients with diabetes have a higher mortality rate after ...