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Malignant pleural mesothelioma : novel biomarkers and related pathways
(2013-03-04)
Malignant mesothelioma is an asbestos induced cancer that is difficult to diagnose. Several studies have combined biomarkers to improve mesothelioma diagnosis, but with moderate success, and there is a need for new ...
Hepatitis C : prevalence, risk factors and implications for screening
(2020-04-17)
Hepatitis C is a blood-borne virus that mainly affects the liver. The infection is often contracted early in life and remains as an asymptomatic slowly progressive disease. The World Health Organization (WHO) has set a ...
Prognostic factors in endometrial cancer
(2022-04-22)
Endometrial cancer (EC) is the most common malignancy of the female reproductive system in Sweden. Patients with EC generally have a good prognosis, though some face recurrence and have a lower survival rate despite ...
Defining the potential of mesothelin-directed CAR T cells for the treatment of ovarian cancer
(2022-09-19)
Chimeric antigen receptor (CAR) T cells have revolutionized the field of immunotherapy, by redirecting T cell specificity and effector functions. Co-stimulation has proven to be crucial for therapeutic effectiveness of CAR ...
Targeting ALK and WIP1 : neuroblastoma precision medicine under development
(2022-10-26)
Neuroblastoma is the childhood solid tumor accountable for the largest number of deaths, calling for improved treatment. Some genetic alterations are considered crucial in driving initiation and progression of neuroblastoma. ...