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Defining the potential of mesothelin-directed CAR T cells for the treatment of ovarian cancer
(2022-09-19)
Chimeric antigen receptor (CAR) T cells have revolutionized the field of immunotherapy, by redirecting T cell specificity and effector functions. Co-stimulation has proven to be crucial for therapeutic effectiveness of CAR ...
Formyl-coenzyme : a transferase, structure and enzymatic mechanism
(2004-08-20)
Background: Formyl-CoA transferase (Frc) is the first enzyme in a two
enzyme pathway responsible for oxalate degradation in Oxalobacter
formigenes. This bacterium is a constitutive part of human intestinal
flora. Its ...
Improving leadership through the power of words and music
(2014-09-18)
Background: Poor leadership is highly prevalent and associated with destructive processes in the workplace, including stress related ill health. Yet, the applied methods to improve leadership practices are rarely grounded ...
Enhanced antiretroviral treatment support in relation to quality of life and virological failure in low income setting : a cluster randomized controlled trial in Quang Ninh, Vietnam
(2013-02-01)
Background: Antiretroviral therapy (ART) has become more widely available in Vietnam since 2005. However, up to now, very little is known about characteristics of people living with HIV (PLHIV) at ART initiation including ...