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Virus Host Interactions in SARS Coronavirus Infection
(2011-10-31)
The global outbreak of Severe Acute Respiratory Syndrome which began in 2002 and ended in 2003 resulted in over 8000 cases in 29 countries, causing an atypical pneumonia which resulted in a case fatality rate of ~10%. The ...
Sarcoidosis : expression of cell regulatory markers and the influence of patient phenotype on bronchoalveolar lavage cell differential counts
(2020-02-21)
Sarcoidosis is a systemic inflammatory disease that can affect almost any organ, but the respiratory system is affected in more than 90% of the cases. To elicit an immune response, an antigen(s) is processed by antigen-presenting ...
Structural enzymology of the biosynthesis of polyketide antibiotics
(2004-05-14)
Anthracyclines are an important group of aromatic antibiotics that exhibit antitumour activity, which makes them useful in treatment of various cancers. They are synthesised in the polyketide biosynthetic pathway as secondary ...
Neutrophil interactions with Streptococcus pyogenes and Staphylococcus aureus
(2017-04-03)
Streptococcus pyogenes and Staphylococcus aureus are Gram-positive bacteria that share many features, including clinical presentations and pathogenic mechanisms, and yet, they still have unique properties. They both cause ...
Clinical and pathophysiological aspects of sepsis
(2014-03-14)
Severe sepsis and septic shock represent challenging problems for the health care system. Despite adequate antibiotics and modern intensive care, severe sepsis is associated with a substantial mortality rate of around 30%, ...
Executive functions and successful behavior
(2021-07-28)
Executive functions are the underlying mechanisms that drive top-down regulation of information processing. While suboptimal executive functions have been investigated in various groups of patients, their impact and ...