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Understanding ageing : the role of mitochondria in determination of caenorhabditis elegans life span
(2011-08-23)
Mitochondria are organelles found in eukaryotic cells. They are involved in many
vital cellular functions. Consequently, mitochondrial dysfunction leads to a variety of human disorders. Many studies of the last 50 years ...
Cellular immunity and inflammation in atherosclerosis
(2001-11-09)
Atherosclerosis, the major cause of death and disability in western countries, is nowadays recognized as an inflammatory disease. Low density lipoprotein (LDL), the major carrier of cholesterol in plasma, is trapped in the ...
Role of macrophage receptor MARCO in host defense
(2003-10-31)
Innate immunity, the first line of defense against infectious microorganisms, appeared early in evolution. Innate immunity relies on specialized cells such as macrophages that are the first to encounter pathogens during ...
Parents who have lost a son or daughter through suicide : towards improved care and restored psychological health
(2013-12-19)
Background: Parents that have lost a son or daughter through suicide are at risk of developing psychological morbidity that may become long-lasting and even life-threatening. Despite this the aftermath of a suicidal loss ...
Molecular mechanisms in vascular inflammation
(2008-01-11)
Vascular inflammation plays an important role in a multitude of major
diseases including sepsis and atherosclerosis. Sepsis has been estimated
to account for more than 100 000 deaths per year in Europe.
Cardiovascular ...
Chemoattractants as causative agents, biomarkers and therapeutic targets in vascular pathology
(2006-09-22)
Atherosclerosis and restenosis are driven by chronic immune response in the vascular wall. This involves cell migration into and within the vessel wall, cell proliferation as well as accumulation of lipids in the vessel ...