Search
Now showing items 1-6 of 6
Cellular immunity and inflammation in atherosclerosis
(2001-11-09)
Atherosclerosis, the major cause of death and disability in western countries, is nowadays recognized as an inflammatory disease. Low density lipoprotein (LDL), the major carrier of cholesterol in plasma, is trapped in the ...
Physical activity, body composition and physical self esteem among children and adolescents
(2005-02-25)
The increasing prevalence of overweight and obesity poses a global health problem. Special concern is focused on overweight during youth since it may cause negative impact on health both during childhood, adolescence and ...
Selling drugs or providing health care? The role of private pharmacies and drugstores, examples from Zimbabwe and Tanzania
(2009-05-22)
Background: In low-income countries many people do not have access to
formal health care because of poverty and weak health systems. Instead
people seek care at private pharmacies and drugstores. Infectious
diseases ...
Involvement of epigenetic mechanisms in disease inheritance and pathogenesis of multiple sclerosis (MS) with a focus on genomic imprinting and DNA methylation in CD4+ T cells
(2017-05-03)
Multiple Sclerosis (MS) is a chronic inflammatory and neurodegenerative disease driven by autoreactive CD4+ T cells. Disease etiology is mediated by a strong interplay between genetic and environmental factors implying a ...
Identification and characterization of a proteasome deubiquitinase inhibitor
(2014-01-10)
The 26S proteasome has emerged as an attractive therapeutic target in the treatment of cancers. Proteasome inhibitors have been shown to selectively kill cancer cells. The FDA approval of bortezomib for the treatment of ...
Dihydroorotate dehydrogenase : new insights into an old target
(2020-01-24)
Purine and pyrimidine nucleotides are important for both biosynthetic and regulatory pathways in cells. As constituents of the DNA and RNA molecules, the requirements for nucleotides in actively dividing cells are increased. ...