Search
Now showing items 1-8 of 8
Cardiovascular comorbidity in rheumatoid arthritis
(2010-10-29)
This thesis is based on four different studies, all focusing on co-morbidities in rheumatoid arthritis. Diabetes mellitus is assessed as a risk factor for rheumatoid arthritis, the temporal relationship between ischemic ...
Effects of lignocaine in endometriosis : a clinical and cellular investigation
(2014-02-17)
BACKGROUND:Endometriosis is a chronic inflammatory disease of unknown origin that can cause severe dysmenorrhea, chronic pain and impaired quality of life. Lignocaine has anti-inflammatory properties and pertubation with ...
Molecular genetic studies of psoriasis susceptibility in 6p21.3
(2005-02-18)
Psoriasis is a common and chronic skin disease with multifactorial background. It affects approximately 2% of the Swedish population and is characterized by inflammatory and scaly lesions. The aetiology of psoriasis is not ...
Viral gastrointestinal infections in allogeneic hematopoietic stem cell transplant patients
(2020-10-16)
Gastrointestinal symptoms, and elevated liver enzymes, are common after HSCT, often due to drug toxicity, graft-versus-host disease (GVHD) or infections. It is essential to distinguish between GVHD and infection, since ...
Beta-amyloid processing and alpha7 neuronal nicotinic acetylcholine receptors in Alzheimer's disease-related mouse models : interactive mechanisms with focus on new drug targets
(2009-04-24)
Accumulation of beta-amyloid (Abeta), neuronal loss and changes in
neurotransmitter systems, in particular the cholinergic system, are
consistent features of Alzheimer s disease (AD). Abeta is thought to play
a critical ...
A study on the role of genes of innate immunity in type 1 diabetes
(2010-02-04)
Type 1 diabetes (T1D) is caused by autoimmune destruction of insulin-producing pancreatic beta-cells. It is a polygenic disease in which maximal genetic susceptibility is conferred by the presence of MHC class II genes. ...
Factors associated with behavioral and psychological symptoms of dementia
(2021-12-22)
Most people with dementia suffer behavioral and psychological symptoms (BPSD). These symptoms add to caregiver stress and accelerate cognitive decline. The etiology of BPSD is complex, with multiple factors influencing ...
Occupational exposure to polycyclic aromatic hydrocarbons and early biomarkers related to cardiovascular disease and cancer
(2019-03-05)
Polycyclic aromatic hydrocarbons (PAH) are omnipresent environmental pollutants composed of fused benzene rings and mainly produced by incomplete combustion of organic material. PAH exposure has been associated with increased ...