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In vivo quantification of extrastriatal dopamine D2 receptors in the human brain
(2005-03-25)
The dopamine D2 receptor subtype attracts considerable attention in research on the patophysiology and drug treatment of several neuropsychiatric disorders, such as schizophrenia and Parkinson's disease. The brain imaging ...
Characterization of the mechanisms of action of anticancer agents in vitro and monitoring their effects in vivo
(2005-02-25)
Chemotherapeutic drug resistance is a major clinical problem and cause for failure in the therapy of human cancer. Mutations in apoptotic programs may promote tumour progression and reduce the efficacy of cancer therapy. ...
Functional characterization of the alternative reading frame protein p14ARF
(2004-05-06)
A deeper understanding of the molecular events underlying tumor development is a prerequisite for the design of novel and efficient therapies. Inactivation of the p53 and retinoblastoma (Rb) tumor suppressor pathways appears ...
International migration and coronary heart disease : epidemiological studies of immigrants in Sweden
(2007-10-05)
In today's globalised world, with considerable international migration,
knowledge about the health of immigrants is becoming increasingly
important. In Sweden, about 13% of the population or over one million
persons are ...