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Drug and alcohol induced hepatotoxicity
(2008-05-23)
Drug induced hepatotoxicity is the most common reason cited for withdrawal of already approved drugs from the market and accounts for more than 50 percent of cases of acute liver failure in the United States. Ethanol (EtOH) ...
Structural basis of cysteine biosynthesis and peptidoglycan remodelling in Mycobacterium tuberculosis
(2013-12-12)
Mycobacterium tuberculosis is the causative agent of tuberculosis, which is responsible for 1.3 million deaths annually. Treatment is difficult due to an elaborate defense machinery, which includes specific metabolic changes ...
Cysteine biosynthesis in Mycobacterium tuberculosis as potential drug target
(2017-04-20)
The bacterium Mycobacterium tuberculosis is the underlying cause of tuberculosis, one of the most devastating infectious diseases, causing 1.4 million deaths in 2015. In addition one third of the global population is ...