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Reasons for non-vaccination
(2006-05-25)
Vaccines are among the most effective public health interventions used today. Population based vaccination programmes are mainly aimed at protecting against common childhood diseases, but other population groups are also ...
Optical based technologies for detection of dental caries
(2009-09-25)
Background: A conservative, non-invasive or minimally invasive approach to clinical management of dental caries requires diagnostic techniques capable of detecting and quantifying lesions at an early stage, when progression ...
Studies on the reliability of biomarkers for alcohol use and abuse
(2013-01-10)
Alcohol is consumed by the vast majority of the population, but prolonged excessive drinking is associated with various negative health and social consequences. It is therefore important to identify individuals with at-risk ...
Guinea pig osteoarthrosis : morphological and biochemical studies
(1999-02-04)
Hartley guinea pigs spontaneously and reproducibly develop an arthropathy mimicking human primary osteoarthrosis. The morphological lesions first appear between 6 and 12 months of age, when it is confined to the ...
The role of the cohesin loader in genome stability : a journey from yeast to human
(2016-10-11)
Structural Maintenance of Chromosome (SMC) complexes, as their name suggests, have a
central role in maintaining the higher structure of genomes, from bacteria to human, and in
doing so protecting their integrity.
...
New molecular markers in mantle cell lymphoma : studies of cannabinoid receptors, 5-lipoxygenase and SOX11
(2010-12-14)
Mantle cell lymphoma (MCL) is a malignant B-cell lymphoma that accounts for 5-10% of all lymphomas and tends to occur in older adults with a higher incidence in males. The genetic hallmark of this neoplasm is the t(11;14) ...
Characterization of the mechanisms of action of anticancer agents in vitro and monitoring their effects in vivo
(2005-02-25)
Chemotherapeutic drug resistance is a major clinical problem and cause for failure in the therapy of human cancer. Mutations in apoptotic programs may promote tumour progression and reduce the efficacy of cancer therapy. ...
Molecular diagnosis of infection with Toxoplasma gondii in immunocompromised patients
(2006-08-23)
The protozoan parasite Toxoplasma gondii infects more than a billion people worldwide. The parasite is generally divided into three clonal lineages, denoted type I, II and III. Primary infections in humans are usually ...
Glomerular expression profiling and novel proteins in normal mouse kidney and adriamycin-induced nephrosis
(2010-08-26)
Kidney glomeruli function as high-capacity molecular sieves through which plasma is filtered into the Bowman s space as primary urine. The glomerular filtration barrier is composed of glomerular endothelial cells, the ...
Epidemiological studies of epilepsy : incidence and risk factors
(2011-10-28)
Epilepsy is one of the most common serious neurological disorders leading to significant consequences for the affected. Despite the wealth of epidemiological data, there are still many un-answered questions. The major ...