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The role of the cohesin loader in genome stability : a journey from yeast to human
(2016-10-11)
Structural Maintenance of Chromosome (SMC) complexes, as their name suggests, have a
central role in maintaining the higher structure of genomes, from bacteria to human, and in
doing so protecting their integrity.
...
Studies on the role of anti-citrullinated protein antibodies in rheumatoid arthritis
(2016-04-06)
Anti-citrullinated protein antibodies (ACPA) are highly specific for rheumatoid arthritis (RA) and present in about two thirds of all patients at diagnosis. They can be detected already before disease onset and have direct ...
Towards new therapeutic targets : identification of novel tumor markers in chronic lymphocytic leukemia
(2010-11-02)
Chronic Lymphocytic Leukemia (CLL) is the most common leukemia in the Western world and is caused by an abnormal accumulation of B lymphocytes in peripheral blood, bone marrow and lymphoid organs. It is a disease mainly ...