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Anaesthesia and analgesia for surgery in rabbits and rats : a comparison of the effects of different compounds
(2008-05-09)
Studies of anaesthesia and analgesia in rats and rabbit were undertaken
with the aim to improve anaesthesia techniques, for better animal welfare
and research quality.
Induction of anaesthesia with the volatile ...
On functions of neurotrophic factors in taste buds and teeth
(2017-11-24)
Background: Chemosensory disorders affect approximately 15% of the U.S. population and an estimated 200,000 individuals visit a doctor each year for problems with their ability to taste or smell (NIDCD). Among the common ...
A study of the transition from premalignancy to clinical prostate cancer
(2005-09-16)
Prostate cancer remains the most commonly diagnosed life-threatening malignancy and the second leading cause of death from cancer in men. However, little is known about molecular mechanisms that underline its initiation ...
Hormonal and paracrine influences on Leydig cell steroidogenesis
(2006-08-18)
Androgen production by Leydig cells is critical for development of the male reproductive organs and for maintaining normal body homeostasis and fertility later in life. Biosynthesis of testosterone is driven by secretion ...
Genetic and functional studies on the thyroid hormone axis
(2008-10-24)
This thesis has two main parts. The first is based on the first three papers with a focus on understanding the etiology and pathogenesis of thyroid malfunction and its effects on different organs. The second is about gaining ...
Tartrate resistant acid phosphatase 5a : a potential regulator of adipocyte cell number and differentiation in white adipose tissue
(2015-04-02)
Tartrate-resistant acid phosphatase (TRAP) exists in two isoforms, TRAP 5a which is monomeric and TRAP 5b which is a dimer generated by proteolytic cleavage of TRAP 5a, that exhibit different functions and localizations. ...
Studies on the links between white adipose tissue phenotype and the circulatory system
(2021-12-22)
Obesity is a strong risk factor for cardiovascular disease. It is defined by an unhealthy excess of white adipose tissue (WAT). Adipose derived weight gains and losses are linked to changes in two other independent ...
The role of estrogens and the microenvironment in lymphoma progression and drug sensitivity
(2017-03-08)
Lymphomas are a group of cancers which originate from lymphatic cells. More than 90% of the lymphomas belong to the group of Non-Hodgkin lymphoma (NHL), which in itself is a non-homogeneous group consisting of different ...
Cognitive behavioral therapy for children and adolescents with dental phobia
(2016-11-08)
Background: Dental phobia is a disabling and clinically significant fear that interferes with the dental care necessary for a child’s or adolescent’s well-being. In fact, the definition of oral health in children and ...
Thioredoxin-1 in Alzheimer disease
(2015-11-05)
Oxidative stress is one of the earliest signs in Alzheimer Disease (AD) brain. In order to protect themselves against oxidative stress, neurons use antioxidants as a defense mechanism. Such an antioxidant is Thioredoxin-1 ...