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Cataract from ultraviolet radiation
(2001-11-09)
Cataract is the major cause of low vision and blindness in the world.
Epidemiological and experimental studies link cataract to (solar)
ultraviolet radiation (UVR) exposure. Current safety limits of UVR
exposure are based ...
Bacteria and cancer : from toxin delivery to carcinogenesis
(2014-02-26)
Epidemiological evidence link certain chronic bacterial infections to a higher risk of cancer development. Induction of an inflammatory circuit and the accumulation of genomic instability are considered mechanisms by which ...
Elicitation and enhancement of T and B cell responses
(2012-10-05)
The Major histocompatibility complex class I (MHC-I) has been characterized in such great depth that a number of its key properties are well understood and part of its behavior can even be predicted. It is therefore ...
Facing the negative impact of cancer treatment on fertility : fertility-related communication and reproductive concerns following a cancer diagnosis
(2015-05-06)
Background: Having children is an important part of life for many men and women. However, cancer treatment may have a negative impact on fertility by, for example, affecting eggs or sperm production. In order to safeguard ...
Cell wall remodeling proteins in Mycobacterium tuberculosis : structure, function and inhibition
(2017-10-27)
The complex and peculiar cell wall architecture is vital for the survival of M. tuberculosis in the host and therefore an established target for several currently used drugs. Understanding of the cell wall maintenance and ...
Immunoregulatory effects of placenta-derived decidual stromal cells
(2016-01-08)
Decidual stromal cells (DSCs) play a pivotal role in feto-maternal tolerance to prevent rejection of the fetus during pregnancy. This provides a rationale for immunomodulatory stromal cells from the placenta being isolated ...
Exercise-induced molecular mechanisms in untrained and life-long highly trained individuals
(2020-08-21)
Regular physical activity results in extensive systemic and functional adaptation effects in the human body that contribute to physical performance, such as muscular strength and endurance, and can have beneficial health ...