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Elicitation and enhancement of T and B cell responses
(2012-10-05)
The Major histocompatibility complex class I (MHC-I) has been characterized in such great depth that a number of its key properties are well understood and part of its behavior can even be predicted. It is therefore ...
Long-term clinical, histological and virological outcomes after sustained virologic response in patients with chronic hepatitis C
(2017-05-09)
Successful antiviral treatment of chronic hepatitis C (HCV), resulting in Sustained Virologic Response (SVR) has been shown to reduce the risk for liver related complications, hepatocellular carcinoma (HCC) and death. ...
Characterization and applications in muscle of a Minicircle vector for Nonviral gene therapy
(2015-05-07)
In gene therapy, the aim is to change the behaviour of a cell by introduction of genetic material, often DNA encoding a protein or a therapeutic RNA. The purpose can be to replace a malfunctioning copy of a gene, as in ...