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Role of transcription factors in sensory neuron specification
(2007-02-09)
The interface between our mind and the internal and external environments is the peripheral nervous system. A range of different sensory neuron subtypes detects cold, heat, pain, touch, and other stimuli. Specialized ...
Biopsies, diagnosis and prognosis in prostate cancer
(2011-11-01)
Prostate cancer is the third most common cancer in men worldwide, and poses a challenge both for patients and health care systems. Many aspects of prostate cancer are controversial, from screening for early detection to ...
Genetic and immunological studies of experimental arthritis, with emphasis on a novel C-type lectin receptor gene complex
(2009-03-05)
Rheumatoid Arthritis (RA) is a chronic, systemic autoimmune syndrome primarily affecting peripheral joints. The etiology of RA is largely unknown but complex interactions between genetic and environmental factors contribute ...
Left ventricular reconstruction in ischemic heart disease
(2007-02-02)
Objectives: [1] To review our experience with left ventricular reconstruction (LVR) regarding safety (early mortality and morbidity) and long-term survival (Study I). [2] To evaluate LVR including surgery for ventricular ...
Introduction of new medicines in Sweden
(2019-08-26)
Payers and providers face challenges in enabling appropriate and sustainable access to new medicines. To help enable rational use of new medicines various policy options exist. In Sweden, horizon scanning, forecasting, ...
Selective insulin signaling in the pancreatic beta-cell via the two insulin receptor isoforms
(2005-02-18)
Insulin exhibits pleiotropic effects that are tissue- as well as development-dependent. However, the mechanisms by which insulin gains selective effects are poorly understood. Selectivity in insulin signaling is currently ...
Hormone-related dietary factors and estrogen/progesterone-receptor defined postmenopausal breast cancer
(2006-11-21)
Breast cancer is the most common invasive cancer among women in Western countries including Sweden. It has been hypothesized that ovarian hormones, such as estrogen and progesterone may, at least partly, play an important ...