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Functional characterization of a peroxisomal acyltransferase gene family
(2008-10-24)
Peroxisomes are cell organelles that play an important role in the metabolism of a variety of lipids including very long chain fatty acids, dicarboxylic acids, bile acids, and xenobiotic carboxylic acids. The metabolism ...
Violence among mentally disordered offenders : risk and protective factors
(2005-05-13)
Background: Violence is one of the leading causes of unnatural deaths, and the consequences of violence for victims, victims families, offenders, and society at large involve extensive suffering and monetary costs. Improving ...
The mammalian peroxisome : ‛its function and distribution’
(2010-12-07)
Peroxisomes are essential organelles for normal cell functions in all organisms from yeast to human. Their important contribution in different metabolic pathways is clearly visible by the severe phenotypes seen in the ...
Complications after total hip arthroplasty : register-based studies on surgical approach and infections
(2014-10-24)
Background: The often excellent outcome of total hip arthroplasty (THA) is sometimes compromised by prosthesis related complications. There is an ongoing debate regarding the effect of surgical approach on prosthesis related ...
Peroxisomal and mitochondrial enzymes involved in lipid metabolism : studies on function and regulation
(2013-11-05)
Fatty acids constitute a major part of the energy that we obtain from the diet and are also the principal source for mammals to store energy. To use the incoming or stored fatty acids as energy, the fatty acids needs to ...
Hormone-related dietary factors and estrogen/progesterone-receptor defined postmenopausal breast cancer
(2006-11-21)
Breast cancer is the most common invasive cancer among women in Western countries including Sweden. It has been hypothesized that ovarian hormones, such as estrogen and progesterone may, at least partly, play an important ...
Acyl-CoA thioesterases : auxiliary enzymes in peroxisomal lipid metabolism
(2007-05-18)
Peroxisomes are small organelles essential for life, which carry out a variety of functions mostly related to lipid metabolism, including α- and β-oxidation as well as the first steps of plasmalogen biosynthesis. Peroxisomal ...
Morbidity and mortality after bariatric surgery in Sweden
(2009-10-02)
Overweight and obesity has increased in Sweden and in the rest of the world during the last decades, probably due to a more sedentary lifestyle and changes in diets. Body mass index (BMI) is a commonly used index of ...
Structural enzymology of the biosynthesis of polyketide antibiotics
(2004-05-14)
Anthracyclines are an important group of aromatic antibiotics that exhibit antitumour activity, which makes them useful in treatment of various cancers. They are synthesised in the polyketide biosynthetic pathway as secondary ...
Pharmacovigilance of mass drug administration for the control of schistosomiasis and soil transmitted helminths in Rwanda
(2023-04-24)
Preventive chemotherapy (PC) is a WHO recommended core interventional measure or a strategy to prevent, control and eliminate STH and schistosomiasis as public health burden by 2030. Though preventable and treatable, they ...