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Chemoattractants as causative agents, biomarkers and therapeutic targets in vascular pathology
(2006-09-22)
plaques, where it colocalized with macrophages, endothelial cells, and smooth muscle cells (SMC). Human coronary artery SMC exposed to either the LTB4 Or the BLT1 partial agonist U75302 exhibited increase of whole-cell ion currents indicating...
A role of sympathetic nervous system in immunomodulation of early experimental African trypanosomiasis
(2004-11-25)
was recorded at 4 h post infection (p. i.) and elevated cortisone and increased splenocyte proliferation, as measured by enzymelinked immunospot assay, radioimmunoassay and thymidineincorporation assay, respectively. Splenic denervation suppressed IFN...
Surgical treatment of left main coronary artery stenosis
(2006-04-28)
ventricular function. There was no aortic incompetence. All angioplasties investigated were patent without signs of restenosis or dilatation. The average dimensions of the LMCA after angioplasty were 4.8 mm and 5.6 mm, and in area 18.9 mm 2 and 24.8 MM2...
Amino acid and protein turnover in human skeletal muscle
(2005-03-25)
Critically ill patients are characterised by a severe net protein catabolism. The rate of muscle protein loss is in the magnitude of 10% per week. A consequence of muscle wasting is increased weakness, which is associated ...
Prevention and treatment of hepatitis B virus infection
(2005-05-06)
surrogate marker for HBV DNA levels in HBeAg-negative carrier mothers. Of 179 sera analysed, eight (4.5%) tested positive for HBeAg, whereas 171 (95.5 %) were HBeAg-negative. Among the HBeAg-negative mothers, nine had H13V DNA levels predefined as high...
Motivating clinical treatment of obesity : methods, education, supervision and outcome
(2004-11-05)
Obesity has become an important health problem worldwide. It increases
the medical risks and affects daily living. Environmental factors such as
diet and sedentary lifestyle are likely to be the cause. In Sweden, the
number ...
Transoesophageal and transthoracic recordings of mitral annulus motion
(2006-02-03)
Maximal systolic and diastolic velocities recorded from four sites of the mitral annulus motion (MAM) reflect left ventricular (LV) performance. This thesis focus on factors influencing M-mode derived velocities in healthy ...
Biosynthesis of leukotriene B4 in hematological malignancies
(2005-05-27)
Leukotrienes (LT) are biologically active metabolites of the fatty acid
arachidonic acid (AA). After liberation of AA by phospholipase A 2 (PLA
2), this fatty acid can be converted to leukotrienes, lipoxins,
prostaglandins ...
Genetic and immunological control of human myasthenia gravis
(2005-09-23)
is in strong linkage with -318C/T and is more frequently present in MG patients with thymoma. MG patients carrying -318C showed significantly decreased expression of CTLA-4 mRNA in non-stimulated cells. In the present study, the relationship of the expression...
Platelets and eosinophils in lung tissue remodelling
(2006-08-25)
Tissue injury and inflammation followed by effective repair restores normal function, but defective repair with associated tissue remodelling and fibrosis can lead to loss of organ function. Thus, interactions between ...