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Amino acid and protein turnover in human skeletal muscle
(2005-03-25)
Critically ill patients are characterised by a severe net protein catabolism. The rate of muscle protein loss is in the magnitude of 10% per week. A consequence of muscle wasting is increased weakness, which is associated ...
Newborn screening for severe primary immunodeficiencies
(2014-09-04)
Primary immunodeficiencies (PID) are congenital disorders of immune competence, which are
mainly characterized by a pathological susceptibility to infection. This is often accompanied by
severe recurrent infections with ...
Immunological consequences of Epstein-Barr virus replication
(2008-04-04)
Epstein-Barr virus (EBV) is a ubiquitous human herpesvirus involved in
the pathogenesis of a wide spectrum of malignant and non-malignant
diseases. In healthy EBV carriers, the virus is believed to infect two
major ...
Origin and ontogeny of human lung macrophages
(2022-05-20)
The lung is a vital organ occupied by a large diversity of immune cells due to its close proximity with the external environment. This thesis focuses on a particular type of immune cell: the macrophage. The lungs are ...
Bacterial sensors and controllers based on organic bioelectronics
(2021-01-14)
Bacterial infections and contaminations are worldwide problems, leading to morbidity and mortality, food waste and economic losses in a variety of industries. The situation is aggravated by the increased occurrence of ...