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Microfluidic electrocapture technology in protein and peptide analysis
(2004-05-19)
After sequencing the genomes of several organisms, science in the postgenomic era now aims at a thorough study of the proteins present in a given tissue or organism. Since this task requires an enormous analytical effort, ...
Cloning and characterization of a p-53-inducible gene, WIG-1
(2001-11-27)
DNA library. The human and mouse WIG-1 coding sequences are 84% identical at the nucleotide level and 86.9% identical at the amino acid level, with the three conserved zinc finger motifs. Two human WIG-1 transcripts of 8 kb and 6 kb were detected by Northern...
Hereditary colorectal cancer : predisposition and prevention
(2004-01-23)
of either a hyperplastic polyp or an adenoma at first colonoscopy
was a predictor for future findings of both types of colon polyps.
In paper III we found that the average perceived benefit of regular
colonoscopies rated 8.0 on the visual analogue scale...
Cytochrome P450 2C9 polymorphism : interindividual differences in drug metabolism and phenotyping methodology
(2002-01-25)
enzyme variant originates from the CYP2C9*1 allele, whereas CYP2C9*2 and CYP2C9*3 code for enzymes with amino acid substitutions R144C and 1359L, respectively. There is accumulating evidence that this genetic polymorphism give rise to clinically important...
Osäkra 'sjukdomar' – dilemman och möjligheter : kvinnliga 'patienters' och läkares erfarenheter av kroniskt trötthetssyndrom och fibromyalgi
(2003-08-08)
This thesis focuses on women with chronic fatigue syndrome (M) and fibromyalgia and how they depict their illness experience. Physicians' experiences of these patient groups have also been examined. This thesis is appropriated ...
Dentin surface conditioning : the role of collagen in dentin bonding
(2001-12-28)
Preparation of dental cavities inevitably produces a thin layer of smear, which covers dentin and enamel surfaces. This smear layer, which is between 1 and 10 gm thick, consists of hydroxyapatite, denatured collagen and ...
Endothelial function and dysfunction in coronary artery bypass grafting
(2002-01-11)
The integrity of the endothelium is of importance for short- and long-term results following coronary artery bypass grafting (CABG). In this thesis different factors of the endothelial role in the regulation of vascular ...
Anterior cruciate ligament reconstruction : patellar tendon, Gore-Tex, Kennedy LAD and tibia tunnel ingrowth
(2003-04-18)
Anterior cruciate ligament injury can induce permanent functional impairment in the physically active individual. Different methods to repair or replace the tom ligament have been tried and investigated. This thesis ...
Synthesis of heterocycles from anthranilic acid and its derivatives
(2004-05-07)
Anthranilic acid (2-aminobenzoic acid, Aa) is the biochemical precursor to the amino acid tryptophan, as well as a catabolic product of tryptophan in animals. It is also integrated into many alkaloids isolated from plants. ...
Endocrine and metabolic aspects of adult Prader Willi syndrome with special emphasis on the effect of growth hormone treatment
(2003-09-05)
Prader Willi Syndrome (PWS) is a complex genetic disorder characterized by muscular hypotonia, hyperphagia, obesity and behavioural problems. Partial growth hormone (GH) deficiency and hypogonadism are common. Results of ...