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Osäkra 'sjukdomar' – dilemman och möjligheter : kvinnliga 'patienters' och läkares erfarenheter av kroniskt trötthetssyndrom och fibromyalgi
(2003-08-08)
This thesis focuses on women with chronic fatigue syndrome (M) and fibromyalgia and how they depict their illness experience. Physicians' experiences of these patient groups have also been examined. This thesis is appropriated ...
Clinical and pathophysiological aspects of intrahepatic cholestasis of pregnancy
(2012-11-20)
Objective: The pathogenesis of intrahepatic cholestasis of pregnancy (ICP) involves impaired bile acid and estrogen/progesterone metabolism and excretion based on genetic and environmental factors. In this thesis we evaluated ...
Sex-different control of hepatic metabolism in relation to insulin sensitivity
(2010-11-18)
The liver is a key metabolic organ. The liver has adapted to the different metabolic needs in men and women, and therefore responds in a sex-specific manner to various stimuli. Specific genes have recently been related to ...
Dissection of virus-host cell interactions in the early response to infection
(2014-09-05)
Stress granules (SG) are dynamic RNA/protein assemblies in the cytoplasm of the cell, formed under conditions of oxidative stress, heat shock or viral infections. These stress conditions trigger a sudden translational ...
Molecular studies on sex differences in hepatic gene expression and fuel metabolism
(2008-08-15)
In nature, sex difference is a multifactorial phenomenon. Although having a genotype of XX or XY determines the sex of an individual, the phenotypic sex differences are orchestrated by multiple factors such as developmental ...