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Cloning and characterization of a p-53-inducible gene, WIG-1
(2001-11-27)
Elucidating the mechanisms by which p53 inhibits tumor growth is a central issue in cancer research, as the TP53 gene is mutated in over half of all human cancers. Lack of functional p53 also contributes to the resistance ...
Social influences on affective responses to negative experiences
(2023-01-25)
As social human beings, the way we emotionally respond to what happens around us is often regulated by our interactions with others. The overall aim of this thesis is to advance the understanding of how social influences ...
Beyond exhaustion and pain : the intertwinement of health and suffering among women and mothers
(2021-11-23)
Aims: The overall goal of the thesis was to understand and to conceptualize health and suffering among women living with exhaustion and long-lasting pain, with a particular focus on motherhood.
Methods: The thesis’ ...
Gene targeting and delivery of therapeutic oligonucleotides
(2017-01-11)
Research in gene therapeutic strategies involving oligonucleotides (ONs) constitutes a growing field with several clinical products already approved and many more under intense investigation. The recent advances have mainly ...