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The effect of galanin message-associated peptide in spinal sensory processing
(1997-11-07)
Galanin message associated peptide (GMAP), the C-terminal flanking peptide in the precursor protein of galanin, has been studied to established whether this peptide has its own biological action. With some exceptions, GMAP ...
Expression and function of GDNF family ligands and receptors in the nervous system
(2001-08-24)
identified and cloned two additional members; GFRalpha2 and GFRalpha3. We characterised the expression pattern of the so far identified ligands and receptors and provided the first evidence of GDNFGFRalpha1 pairing in vivo, showing that GDNF-/- mice were...
Renal insufficiency, mortality and myocardial infarction
(2008-05-09)
for the highest versus the lowest quartile of the apoB/apoA-1 ratio was 2.88 (2.54 to 3.26) compared to HR, 3.35 (2.25 to 4.91) for those with CKD. After adjustment for the total cholesterol/ high-density lipoprotein cholesterol ratio, an increase by one standard...
Oxidoreductases and RNA degradosome controlling virulence-associated traits of Salmonella enterica serovar Typhimurium
(2013-09-04)
The oxidative stress response is a fundamental and primitive mode of innate immune defense in nearly all forms of life. The host oxidative stress response becomes truly important and effective especially against intracellular ...
Responsive nanostructured materials for bioanalyte detection and triggered antimicrobial therapy
(2022-04-29)
SiO2 dielectric spacer to control the average spacing between spherical silver nanoparticles in the synthesised nanoaggregates the optical and photothermal behaviour of the nanoaggregates can be tuned into the near-IR. The effectiveness...
Cost analysis and policy implications in psychiatric care
(2009-04-01)
in Sweden in 2001 (Study I) was estimated at MSEK 85 774 (M€ 9 426, €1= SEK9.1). Indirect costs were totally predominant and constituted about 80% of the total cost, i.e. production losses due to early retirement, sickness absence and premature death...
Toll-like receptor-induced cytokine secretion by human monocytes in healthy donors and septic patients assessed at the single cell level
(2013-08-23)
Following the ligation of Toll-like receptors (TLRs) by bacterial-derived signature molecules, innate immune cells such as monocytes, macrophages and neutrophils initiate the inflammatory process by secreting chemokines ...
Effects of DNA damage and vesicular exchange in P. falciparum
(2019-05-28)
are previously characterized for their enhanced capacity to generate EVs. In this study, we discovered that EVs originated from infected cell contain a subset of host miRNAs and the Ago2 proteins. These EVs are readily internalized by endothelial cells...