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Responsive nanostructured materials for bioanalyte detection and triggered antimicrobial therapy
(2022-04-29)
Inorganic nanomaterials are attractive candidates for biomedicine as they can offer increased stability including light, temperature and chemical stability while also offering the benefits of high-throughput synthetic ...
Processing, stability and interactions of lung surfactant protein C
(2005-11-23)
Mature SP-C is a 4.2 kDa transmembrane protein which is uniquely expressed in the alveolar type II cell. Human SP-C is generated via multistep proteolytic cleavage of both the C-terminal and Nterminal regions of proSP-C. ...
Mechanisms of cancer cell death by mutant p53-reactivating compound APR-246
(2021-02-11)
Tumor suppressor TP53 is the most frequently mutated gene in cancer. A majority of TP53 mutations result in a mutant p53 that disrupts its DNA binding capabilities but may also acquire novel gain-of-function activities ...